Size??100ul
Cat code??220022
Species Cross-reactivity??H
Key Application??WB
Host??Mouse
Clone Number??4E8-C9-D4
Antibody type??Monoclonal antibody
Purified method??
Isotype??IgG1
Molecular Weight??41kDa
Sensitivity??The antibody detects endogenous level of total KRT19 protein.
Immunogen??Purified recombinant fragment of human KRT19 expressed in E. Coli.
UniProt Number??P08727
GeneBank ID??NM_002276.4
Subcellular location??
Formulation??Ascitic fluid containing 0.03% sodium azide.
Altername??40 kDa keratin intermediate filament ; CK 19 ; CK-19 ; ck19 ; Cytokeratin 19 ; Cytokeratin-19 ; k19 ; K1C19_HUMAN ; k1cs ; Keratin 19 ; Keratin type I 40 kD ; Keratin type i 40kD ; Keratin type I cytoskeletal 19 ; Keratin, type I cytoskeletal 19 ; Keratin, type I, 40 kd ; Keratin-19 ; krt19 ; mgc15366 ;
Gene_symbol??K19; CK19; K1CS
Summary??The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]
UniPort summary  Function??Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
Application Images :??
Western blot detection of KRT19 antibody in CaCo2, HepG2 and T-47D cell lysates using KRT19 antibody(dilution 1:500).Predicted band size:41KDa.Observed band size:41KDa.