SANT-1
產品名稱： SANT-1
英文名稱：
產品編號： SM-0008-0010
產品價格： 0
產品產地： 以色列
品牌商標： Biological industries（BI）
更新時間： null
使用范圍： null
- 聯系人 : 市場部
- 地址 : 上海市奉賢區匯豐西路2082號9幢
- 郵編 : 200120
- 所在區域 : 上海
- 電話 : 189****5545 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@xpbiomed.com
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Product Description
SANT-1 is a potent antagonist of Smoothened (Smo), which in turn inhibits Hedgehog (Hh) signaling, specifically targeting Shh-LIGHT2 (IC50?of 20nM) and SmoA1-LIGHT2 (IC50?of 30nM). As Smoothened mediates Hedgehog activity, SANT-1 has the potential of affecting cellular patterning through differentiation and proliferation during embryonic development (Chen, et al.). When used in conjunction with CHIR99021 (Cat. No. SM-0001-0010), LDN193189 (Cat. No. SM-0005-0010), and Y27632 (Cat. No. SM-0013-0010), among others, SANT-1 aids in the generation of functional human pancreatic beta cells from human pluripotent stem cells (PSCs) (Pagliuca, et al.) in addition to the creation of pancreatic progenitors from PSCs (Nostro, et al.).
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Product Synonyms:
Shh signaling antagonist V
Constructed from renowned protocols, Biological Industries selection of small molecules will streamline workflows for research in diabetes, neural disorders, and cardiovascular disease.
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?產品官網鏈接：https://www.bioind.com/worldwide/sant-1/
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