SMAD3 monoclonal antibody, clone AF9F7
產品名稱: SMAD3 monoclonal antibody, clone AF9F7
英文名稱: SMAD3 monoclonal antibody, clone AF9F7
產品編號: MAB2701
產品價格: null
產品產地: 臺灣
品牌商標: Abnova
更新時間: null
使用范圍:
亞諾法生技股份有限公司(Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against recombinant SMAD3.
- Immunogen:
- Recombinant His fusion protein corresponding to human SMAD3.
- Host:
- Mouse
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- GSK-3beta regulates cyclin D1 expression: a new target for chemotherapy.
Takahashi-Yanaga F, Sasaguri T.Cell Signal. 2008 Apr;20(4):581-9. Epub 2007 Oct 23.
- 2.
- Targeting cyclins and cyclin-dependent kinases in cancer: lessons from mice, hopes for therapeutic applications in human.
Lee YM, Sicinski P.Cell Cycle. 2006 Sep;5(18):2110-4. Epub 2006 Sep 15.
- 3.
- Mammalian cyclin-dependent kinases.
Malumbres M, Barbacid M.Trends Biochem Sci. 2005 Nov;30(11):630-41. Epub 2005 Oct 19.
- Entrez GeneID:
- 4088
- Gene Name:
- SMAD3
- Gene Alias:
- DKFZp586N0721,DKFZp686J10186,HSPC193,HsT17436,JV15-2,MADH3,MGC60396
- Gene Description:
- SMAD family member 3
- Omim ID:
- 603109
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. [provided by RefSeq
- Other Designations:
- MAD, mothers against decapentaplegic homolog 3,SMA- and MAD-related protein 3,SMAD, mothers against DPP homolog 3,mad homolog JV15-2,mad protein homolog,mothers against decapentaplegic homolog 3
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Anemia, Sickle Cell
- Anemia, sickle cell
- Asthma
- Bacteremia
- Breast cancer
- Breast Neoplasms
- Cleft Lip
- Cleft Palate
- Coronary Artery Disease
- Crohn Disease
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Diabetic Nephropathies
- Genetic Predisposition to Disease
- Graft vs Host Disease
- Head and Neck Neoplasms
- Hypersensitivity

