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Human Growth Factors & Cytokines
Recombinant Human TL-1A





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		Synonyms :
TNFSF15, VEGI



		Description :
TL-1A belongs to the TNF superfamily of ligands.  It is expressed predominantly in endothelial cells, and to a lesser extent in placenta, lung, kidney, skeletal muscle, pancreas, small intestine and colon.  TL-1A inhibits endothelial cell proliferation and angiogenesis, and has been shown to induce NFkB activation, caspase activity, and apoptosis in responding cell lines.  TL-1A interacts with TNFRSF25/DR3 receptor, but can also bind to a decoy receptor TNFRSF21/DR6.  Recombinant human TL-1A is a 22.0 kDa polypeptide of 194 amino acid residues.



		Catalog #:
310-23



		Source :
E.coli



		Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses.



		Endotoxin Level :
Endotoxin level is less than 0.1 ng per μg (1EU/μg).



		Biological Activity :
Determined by its ability to stimulate IFN-γ production by human PBMC using a concentration range of 10.0-100.0 ng/ml.  Note: Results may vary with PBMC donors.


Selected References :
Selected List of References Citing This PeproTech Product



                AA Sequence :
QLRAQGEASV QFQALKGQEF APSHQQVYAP LRADGDKPRA HLTVVRQTPT QHFKNQFPAL HWEHELGLAF TKNRMNYTNK FLLIPESGDY FIYSQVTFRG MTSECSEIRQ AGRPNKPDSI TVVITKVTDS YPEPTQLLMG TKSVCEVGSN WFQPIYLGAM FSLQEGDKLM VNVSDISLVD YTKEDKTFFG AFLL 



		PubMed Link :
TNFSF15


Country of Origin :
USA
















        Size A
5μg
$80?
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        Size B
20μg
$195?
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        Size C
1mg
$3000?
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Special 
                    Sizes: 
 Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.





Usage:
For Research Use Only.  Not for use in diagnostic or therapeutic procedures.