Biotinylated IgG Fraction Polyclonal Antibody against Beta Amyloid (Aβ) 42-抗體-抗體-生物在線
翌圣生物科技（上海）股份有限公司
Biotinylated IgG Fraction Polyclonal Antibody against Beta Amyloid (Aβ) 42

Biotinylated IgG Fraction Polyclonal Antibody against Beta Amyloid (Aβ) 42

商家詢價

產品名稱： Biotinylated IgG Fraction Polyclonal Antibody against Beta Amyloid (Aβ) 42

英文名稱： Biotinylated IgG Fraction Polyclonal Antibody against Beta Amyloid (Aβ) 42

產品編號： SIG-39135

產品價格： 詢價

產品產地： USA

品牌商標： COVANCE

更新時間： 2024-12-10T13:18:22

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翌圣生物科技（上海）股份有限公司
  • 聯系人 : 李自轉
  • 地址 : 上海市浦東新區天雄路166弄一號樓三層南單元
  • 郵編 : 200030
  • 所在區域 : 上海
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Description β-Amyloid 42 Polyclonal Antibody, Biotin Labeled IgG Fraction (SIGNET) - SIGNET ANTIBODIES Biotinylated IgG Fraction Polyclonal Antibody against Beta Amyloid (Aβ) 42
(Formerly Signet Catalog Nos.: 9135-02, 9135-05, 9135-10)
Intended Use **Research Use Only (RUO)**

This product is sold for laboratory research use only, not for human or in-vivo use.
Form Biotin Labeled IgG Fraction (Stored in PBS + 50% Glycerol; no preservatives or carrier proteins)
Host Rabbit
Specificity β-Amyloid 42 Polyclonal Antibody, Biotin Labeled IgG Fraction (SIGNET) - SIGNET ANTIBODIES Signet’s rabbit anti beta amyloid (Aβ) 42 antibody is specific for the C-terminus of Aβ 42. The rabbit anti Aβ 42 reacts extremely well with the 42 isoform. The rabbit anti Aβ 42 antibody does not cross-react with Aβ 40 or APP. Altered levels of Aβ isoforms, specifically the Aβ 40 and Aβ 42 have been shown in the brain tissues and CSF of Alzheimer’s Disease patients.

This antibody was generated against a peptide conjugated to keyhole limpet hemocyanin.
Uses β-Amyloid 42 Polyclonal Antibody, Biotin Labeled IgG Fraction (SIGNET) - SIGNET ANTIBODIES This antibody is effective in immunohistochemistry (IHC).
Suggested Working Dilution β-Amyloid 42 Polyclonal Antibody, Biotin Labeled IgG Fraction (SIGNET) - SIGNET ANTIBODIES The optimal working dilution should be determined for each specific assay condition.
  • IHC:
    Pretreatment: The epitope must be re-exposed in fixed tissue by pretreatment of tissue using formic acid (70%) for 10-30 minutes at room temperature
Storage β-Amyloid 42 Polyclonal Antibody, Biotin Labeled IgG Fraction (SIGNET) - SIGNET ANTIBODIES Do not store antibody diluted below 50 ug/mL in the absence of protein (i.e.: add 2% bovine serum albumin). The antibody is best stored undiluted at -20°C to -70°C.
References Mehta PD, et al. Amyloid beta protein 40 and 42 levels in matched cerebrospinal fluid and plasma from patients with Alzheimer disease. Neurosci Lett 304(1-2):102-6, 2001.

Schupf N, et al. Elevated plasma amyloid beta-peptide 42 and onset of dementia in adults with Down syndrome. Neurosci Lett 301(3):199-203, 2001.

Mehta PD, et al. Plasma and cerebrospinal fluid levels of amyloid beta proteins 40 and 42 in Alzheimer disease. Arch Neurol 57(1):100-5, 2000.

Tapiola T, et al. Relationship between apoE genotype and CSF beta-amyloid (42) and tau in patients with probable and definite Alzheimer's disease. Neurobiol Aging 21(5):735-40, 2000.

Emmerling MR, et al. Traumatic brain injury elevates the Alzheimer's amyloid peptide A beta 42 in human CSF. A possible role for nerve cell injury. Ann NY Acad Sci 903:118-22, 2000.

Potempska A, et al. Quantification of sub-femtomole amounts of Alzheimer amyloid beta peptides. Amyloid 6(1):14-21, 1999.

Mayeux R, et al. Plasma amyloid beta-peptide 42 and incipient Alzheimer's disease. Ann Neurol. 46(3):412-6, 1999.
Warranty/Conditions β-Amyloid 42 Polyclonal Antibody, Biotin Labeled IgG Fraction (SIGNET) - SIGNET ANTIBODIES Covance products may not be resold or modified for resale without prior written approval.
Rev. Date β-Amyloid 42 Polyclonal Antibody, Biotin Labeled IgG Fraction (SIGNET) - SIGNET ANTIBODIES 4/8/2007