Recombinant Human RANTES (CCL5)
 
Catalog Number:
AF-300-06
Synonyms:
Regulation upon Activation Normal T cell Express Sequence, CCL5, SIS-delta
Description:
RANTES is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV). Recombinant human RANTES is a 7.8 kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines. Manufactured using all non-animal reagents.
AA Sequence:
SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEMS
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
Determined by its ability to chemoattract human blood monocytes using a concentration range of 1.0-10.0 ng/ml.
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Research Interests:
AIDS / HIV
Angiogenesis/ Cardiovascular
Chemotaxis
Immune System
Inflammation
Neurobiology
Wound Healing
Allergy
Transplantation
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Country of Origin:
USA
Research Use Only. Not for use in diagnostic or therapeutic procedures.