HLA-B monoclonal antibody, clone EP-4-抗體-抗體-生物在線
亞諾法生技股份有限公司（Abnova)
HLA-B monoclonal antibody, clone EP-4

HLA-B monoclonal antibody, clone EP-4

商家詢價

產品名稱： HLA-B monoclonal antibody, clone EP-4

英文名稱： HLA-B monoclonal antibody, clone EP-4

產品編號： MAB5202

產品價格： null

產品產地： 臺灣

品牌商標： Abnova

更新時間： null

使用范圍：

亞諾法生技股份有限公司（Abnova)
  • 聯系人 :
  • 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
  • 郵編 : 11493
  • 所在區域 : 臺灣
  • 電話 : +886-920**1152 點擊查看
  • 傳真 : 點擊查看
  • 郵箱 : sales@abnova.com.tw

  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native HLA-B.
  • Immunogen:
  • Native purified from lymphocytes of HLA-B27 individual.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • EP-4 recognizes the HLA-B27 cell surface antigen on human cells. Since EP-4 recognizes the HLA-B27 antigen, it may be used to HLA type human lymphoctyes. Approximately 60% of patients with ankylosing spondylitis are HLA-B27 positive. This reagent can be used to help identify this HLA haplotype in human lymphocytes. Monoclonal antibody EP-4 recognizes the HLA-B27 antigen expressed on individuals with this HLA haplotype.
  • Form:
  • Liquid
  • Isotype:
  • IgM, kappa
  • Storage Buffer:
  • In PBS (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Flow Cytometry
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 3106
  • Gene Name:
  • HLA-B
  • Gene Alias:
  • AS,HLA-B-7301,HLA-B73,HLAB,HLAC,SPDA1
  • Gene Description:
  • major histocompatibility complex, class I, B
  • Gene Summary:
  • HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described. [provided by RefSeq
  • Other Designations:
  • HLA class I histocompatibility antigen, B alpha chain,HLA class I histocompatibility antigen, B-7 alpha chain,HLA class I histocompatibility antigen, Cw-5 alpha chain,HLA-B alpha chain (HLA-B*7301),MHC Class I HLA heavy chain,MHC HLA-B cell surface glycop
  • Related Disease