FGF19細(xì)胞因子
產(chǎn)品名稱： FGF19細(xì)胞因子
英文名稱：
產(chǎn)品編號(hào)： IMF-F19
產(chǎn)品價(jià)格： 0
產(chǎn)品產(chǎn)地： 廈門/IMMOCELL
品牌商標(biāo)： IMMOCELL
更新時(shí)間： 2023-08-17T17:21:32
使用范圍： null
廈門逸漠生物科技有限公司
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Backgound Fibroblast growth factor-19 (FGF19) belongs to the large FGF family which has at least 23 members. All FGF family members are heparin binding growth factors with a core 120 amino acid (a.a.) FGF domain that allows for a common tertiary structure. FGFs are expressed during embryonic development and in restricted adult tissues. Four distinct but related classes of FGF receptors, FGF R1, 2, 3, and 4 exist. Unlike most FGFs which bind to and activate more than one FGF receptor, FGF19 is a specific ligand for FGF R4. Source Recombinant Human FGF-19 is expressed from Escherichia coli. It contains AA Leu 25 - Lys 216. The protein has a calculated MW of 24.2 kDa. This protein carries a polyhistidine tag at the N-terminus. Recombinant Human FGF-19 is expressed from Escherichia coli Endotoxin Less than 1.0 EU per μg by the LAL method. AA Sequence MRPLAFSDAG PHVHYGWGDP IRLRHLYTSG PHGLSSCFLR IRADGVVDCA RGQSAHSLLE IKAVALRTVA IKGVHSVRYL CMGADGKMQG LLQYSEEDCA FEEEIRPDGY NVYRSEKHRL PVSLSSAKQR QLYKNRGFLP LSHFLPMLPM VPEEPEDLRG HLESDMFSSP LETDSMDPFG LVTGLEAVRS PSFEK Purity Purity >95% as determined by SDS-PAGE. Formulation Lyophilized from 0.22 μm filtered solution in PBS, 0.3 M NaCl, 0.3 M Arginine, pH7.4. Normally trehalose is added as protectant before lyophilization. Reconstitution Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20°C. Further dilutions should be made in appropriate buffered solutions. Storage For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. SDS-PAGE Human FGF-19, His Tag on SDS-PAGE under reducing (R) condition Human FGF-19, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.