PeproTech重組人Fetuin A/AHSG 100ug
產(chǎn)品名稱: PeproTech重組人Fetuin A/AHSG 100ug
英文名稱: Recombinant Human Fetuin A/AHSG
產(chǎn)品編號(hào): 140-13
產(chǎn)品價(jià)格: 0
產(chǎn)品產(chǎn)地: 美國(guó)
品牌商標(biāo): PeproTech
更新時(shí)間: null
使用范圍: null
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- 所在區(qū)域 : 江蘇
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Recombinant Human Fetuin A/AHSG
Catalog Number:140-13Synonyms:Alpha-2-HS-glycoprotein, Alpha-2-Z-globulin, Ba-alpha-2-glycoprotienDescription:Fetuin A/AHSG is a human plasma glycoprotein belonging to the Cystatin family of proteases inhibitors. It is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes/macrophages. Fetuin A/AHSG is a major serum protein component that exerts various calcium dependent physiological activities, and can mediate growth signaling in certain tumor cells. It also can act as a natural antagonist against specific TGF-β and BMP signaling proteins, Recombinant human Fetuin-A is a heterodimeric protein containing a 282 amino acid A chain and a 27 amino acid B chain. Due to glycosylation, recombinant Fetuin-A migrates at an apparent molecular weight of 45 – 55 kDa by SDS-PAGE run under non-reducing conditions.AA Sequence:APHGPGLIYR QPNCDDPETE EAALVAIDYI NQNLPWGYKH TLNQIDEVKV WPQQPSGELF EIEIDTLETT CHVLDPTPVA RCSVRQLKEH AVEGDCDFQL LKLDGKFSVV YAKCDSSPDS AEDVRKVCQD CPLLAPLNDT RVVHAAKAAL AAFNAQNNGS NFQLEEISRA QLVPLPPSTY VEFTVSGTDC VAKEATEAAK CNLLAEKQYG FCKATLSEKL GGAEVAVTCT VFQTQPVTSQ PQPEGANEAV PTPVVDPDAP PSPPLGAPGL PPAGSPPDSH VLTVVQPSVG AAAGPVVPPC PGRIRHFKVSource:HEK293 cellsPurity:Greater than 98% by SDS-PAGE gel and HPLC analyses.Biological Activity:Determined by its ability to inhibit Cathespin V cleavage of a fluorogenic peptide substrate Z-LR-AMC (RLUs). The expected IC50 is ≤ 100nM.????Research Interests:??Country of Origin:USAResearch Use Only. Not for use in diagnostic or therapeutic procedures.
