Recombinant Murine IL-1β
產品名稱： Recombinant Murine IL-1β
英文名稱： Recombinant Murine IL-1β
產品編號： 211-11B
產品價格： 0
產品產地： USA
品牌商標： peprotech
更新時間： null
使用范圍： null
上海研卉生物科技有限公司
- 聯系人 :
- 地址 : 上海市嘉定區葉城路1288號
- 郵編 :
- 所在區域 : 上海
- 電話 : 187****6455 點擊查看
- 傳真 : 點擊查看
- 郵箱 : yanhuibio@163.com
Recombinant Murine IL-1β
產品編號:
211-11B
別名:
Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
描述:
IL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant murine IL-1β is a 17.5 kDa protein containing 153 amino acid residues.
氨基酸序列:
MVPIRQLHYR LRDEQQKSLV LSDPYELKAL HLNGQNINQQ VIFSMSFVQG EPSNDKIPVA LGLKGKNLYL SCVMKDGTPT LQLESVDPKQ YPKKKMEKRF VFNKIEVKSK VEFESAEFPN WYISTSQAEH KPVFLGNNSG QDIIDFTMES VSS
來源:
E.coli
純度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
生物活性:
The ED50 as determined by the dose-dependent stimulation of murine D10S cells is ≤ 0.002 ng/ml, corresponding to a specific activity of ≥ 5 x 108 units/mg.
?
?
?
?
交叉反應:
Human, Monkey, Pig, Rat, Mouse + Chicken