SNCAIP (C-term) Peptide
產品名稱： SNCAIP (C-term) Peptide
英文名稱： SNCAIP (C-term) Peptide
產品編號： P2059
產品價格： 0
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍： null
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of SNCAIP.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human SNCAIP.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotective.
Tanaka M, Kim YM, Lee G, Junn E, Iwatsubo T, Mouradian MM.J Biol Chem. 2004 Feb 6;279(6):4625-31. Epub 2003 Nov 19.
- 2.
- Casein kinase II-mediated phosphorylation regulates alpha-synuclein/synphilin-1 interaction and inclusion body formation.
Lee G, Tanaka M, Park K, Lee SS, Kim YM, Junn E, Lee SH, Mouradian MM.J Biol Chem. 2004 Feb 20;279(8):6834-9. Epub 2003 Nov 26.
- 3.
- Siah-1 facilitates ubiquitination and degradation of synphilin-1.
Nagano Y, Yamashita H, Takahashi T, Kishida S, Nakamura T, Iseki E, Hattori N, Mizuno Y, Kikuchi A, Matsumoto M.J Biol Chem. 2003 Dec 19;278(51):51504-14. Epub 2003 Sep 23.
- Entrez GeneID:
- 9627
- Protein Accession#:
- NP_005451.1
- Gene Name:
- SNCAIP
- Gene Alias:
- MGC39814,SYPH1
- Gene Description:
- synuclein, alpha interacting protein
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The encoded protein interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration. A mutation in this gene has been associated with Parkinson's disease. Alternatively spliced transcript variants encoding different isoforms of this gene have been described, but their full-length nature has yet to be determined. [provided by RefSeq
- Other Designations:
- synphilin,synphilin-1,synuclein alpha interacting protein
- Gene Pathway