Recombinant Human Beta-NGF (Mammalian)
產(chǎn)品名稱： Recombinant Human Beta-NGF (Mammalian)
英文名稱：
產(chǎn)品編號(hào)： CI51
產(chǎn)品價(jià)格： 0
產(chǎn)品產(chǎn)地： 中國
品牌商標(biāo)： Novoprotein
更新時(shí)間： null
使用范圍： null
蘇州近岸蛋白質(zhì)科技股份有限公司
- 聯(lián)系人 : 蘇州近岸蛋白質(zhì)科技股份有限公司
- 地址 : 上海市浦東新區(qū)伽利略路11號(hào)
- 郵編 : 201203
- 所在區(qū)域 : 江蘇
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Human β-Nerve Growth Factor (β-NGF) was initially isolated in the mouse submandibular gland. It is composed of three non-covalently linked subunits α, β, and γ; it exhibits all the biological activities ascribed to NGF. It is structurally related to BDNF, NT-3 and NT-4 and belongs to the cysteine-knot family of growth factors that assume stable dimeric structures. Β-NGF is a neurotrophic factor that signals through its receptor β-NGF, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. Β-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. These results suggest that β-NGF is a pleiotropic cytokine, which in addition to its neurotropic activities may have an important role in the regulation of the immune system. Human β-NGF shares 90% sequence similarity with mouse protein and shows cross-species reactivity.