生物素標記 人 磷脂酰肌醇蛋白聚糖 2 蛋白, 組氨酸,Avi標簽
產(chǎn)品名稱: 生物素標記 人 磷脂酰肌醇蛋白聚糖 2 蛋白, 組氨酸,Avi標簽
英文名稱: Biotinylated Human Glypican 2 Protein, His,Avitag?
產(chǎn)品編號: GP2-H82E3
產(chǎn)品價格: 13800
產(chǎn)品產(chǎn)地: 中國
品牌商標: 北京百普賽斯生物科技股份有限公司
更新時間: 2025-09-19T18:06:11
使用范圍: null
| 規(guī)格 | 價格 |
| 200ug |
- 聯(lián)系人 : 團子
- 地址 : 北京經(jīng)濟技術開發(fā)區(qū)宏達北路8號5號樓4層
- 郵編 : 100176
- 所在區(qū)域 : 北京
- 電話 : 151****8562 點擊查看
- 傳真 : 點擊查看
- 郵箱 : order.cn@acrobiosystems.com
- 二維碼 : 點擊查看
Glypican 2 (GPC2), also known cerebroglycan, is a glycophosphatidylinositol-linked integral membrane heparan sulfate proteoglycan found in the developing nervous system. Cerebroglycan participates in cell adhesion and is thought to regulate the growth and guidance of axons. Cerebroglycan has especially high affinity for laminin-1. GPC2 silencing inactivates Wnt/β-catenin signaling and reduces the expression of N-Myc, an oncogenic driver of neuroblastoma tumorigenesis. Immunotoxins and chimeric antigen receptor (CAR) T cells targeting GPC2 inhibit neuroblastoma growth in mouse models. A GPC3 specific antibody drug conjugate (ADC) can also inhibit neuroblastoma cell proliferation.
