SMAD1 monoclonal antibody (M04A), clone 2A1
產品名稱： SMAD1 monoclonal antibody (M04A), clone 2A1
英文名稱： SMAD1 monoclonal antibody (M04A), clone 2A1
產品編號： H00004086-M04A
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a full-length recombinant SMAD1.
- Immunogen:
- SMAD1 (AAH01878.1, 1 a.a. ~ 465 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPGQPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQPNSHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGSQPMDTNMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS
- Host:
- Mouse
- Reactivity:
- Human, Mouse, Rat
- Isotype:
- IgG2b Kappa
- Storage Buffer:
- In ascites fluid
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (76.89 KDa) .
- MSDS:
Download
- Applications
- Western Blot (Cell lysate)
- SMAD1 monoclonal antibody (M04A), clone 2A1 Western Blot analysis of SMAD1 expression in HeLa ( Cat # L013V1 ).
- Protocol Download
- Western Blot (Cell lysate)
- SMAD1 monoclonal antibody (M04A), clone 2A1. Western Blot analysis of SMAD1 expression in PC-12 ( Cat # L012V1 ).
- Protocol Download
- Western Blot (Cell lysate)
- SMAD1 monoclonal antibody (M04A), clone 2A1. Western Blot analysis of SMAD1 expression in NIH/3T3 ( Cat # L018V1 ).
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Entrez GeneID:
- 4086
- GeneBank Accession#:
- BC001878
- Protein Accession#:
- AAH01878.1
- Gene Name:
- SMAD1
- Gene Alias:
- BSP1,JV4-1,JV41,MADH1,MADR1
- Gene Description:
- SMAD family member 1
- Omim ID:
- 601595
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq
- Other Designations:
- MAD, mothers against decapentaplegic homolog 1,Mad-related protein 1,SMAD, mothers against DPP homolog 1,Sma- and Mad-related protein 1,TGF-beta signaling protein 1,mothers against DPP homolog 1,transforming growth factor-beta signaling protein 1
- Gene Pathway
- Related Disease
- Cleft Lip
- Cleft Palate
- Diabetes Mellitus, Type 1
- Diabetic Nephropathies
- Genetic Predisposition to Disease
- Head and Neck Neoplasms
- Hemochromatosis
- Hypertension, Pulmonary
- Kidney Failure, Chronic
- Neoplasm Recurrence, Local
- Neoplasms, Second Primary
- Obesity
- Ovarian Failure, Premature
- Polycystic Ovary Syndrome
- Puberty, Delayed
- Puberty, Precocious
- Thrombophilia
- Tobacco Use Disorder