ATF2 (phospho T51) polyclonal antibody
產(chǎn)品名稱： ATF2 (phospho T51) polyclonal antibody
英文名稱： ATF2 (phospho T51) polyclonal antibody
產(chǎn)品編號： PAB0413
產(chǎn)品價格： null
產(chǎn)品產(chǎn)地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯(lián)系人 :
- 地址 : 臺灣臺北市內(nèi)湖區(qū)洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區(qū)域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of ATF2.
- Immunogen:
- Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T51 of human ATF2.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein A purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Dot Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Biliverdin reductase, a novel regulator for induction of activating transcription factor-2 and heme oxygenase-1.
Kravets A, Hu Z, Miralem T, Torno MD, Maines MD.J Biol Chem. 2004 May 7;279(19):19916-23. Epub 2004 Feb 25.
- 2.
- Activation and interaction of ATF2 with the coactivator ASC-2 are responsive for granulocytic differentiation by retinoic acid.
Hong S, Choi HM, Park MJ, Kim YH, Choi YH, Kim HH, Choi YH, Cheong J.J Biol Chem. 2004 Apr 23;279(17):16996-7003. Epub 2004 Jan 20.
- 3.
- Induction of CHOP expression by amino acid limitation requires both ATF4 expression and ATF2 phosphorylation.
Averous J, Bruhat A, Jousse C, Carraro V, Thiel G, Fafournoux P.J Biol Chem. 2004 Feb 13;279(7):5288-97. Epub 2003 Dec 1.
- Applications
- Dot Blot (Peptide)
- Dot blot analysis of ATF2 (phospho T51) polyclonal antibody (Cat # PAB0413) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentration was 0.5 ug/mL. P-Pab : phospho-antibody; P-Peptide : phospho-peptide; NP-Peptide : non-phospho-peptide.
- Entrez GeneID:
- 1386
- Protein Accession#:
- NP_001871;A1L3Z2
- Gene Name:
- ATF2
- Gene Alias:
- CRE-BP1,CREB2,HB16,MGC111558,TREB7
- Gene Description:
- activating transcription factor 2
- Omim ID:
- 123811
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined. [provided by RefSeq
- Other Designations:
- OTTHUMP00000163262,activating transcription factor 2 splice variant ATF2-var2,cAMP responsive element binding protein 2, formerly
- Gene Pathway