Anti-Protocadherin Gamma B2 mAb: ATTO 488 [S148-30]-抗體-抗體-生物在線

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StressMarq
Anti-Protocadherin Gamma B2 mAb: ATTO 488 [S148-30]

Anti-Protocadherin Gamma B2 mAb: ATTO 488 [S148-30]

商家詢價(jià)

產(chǎn)品名稱: Anti-Protocadherin Gamma B2 mAb: ATTO 488 [S148-30]

英文名稱: Protocadherin Gamma B2 Monoclonal Antibody: ATTO 488 [S148-30]

產(chǎn)品編號(hào): SMC-452D-A488

產(chǎn)品價(jià)格: null

產(chǎn)品產(chǎn)地: 加拿大

品牌商標(biāo): StressMarq

更新時(shí)間: null

使用范圍: WB, ICC

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Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. The protocadherein gamma cluster consists of three subfamilies (A, B and C). As a member of the gamma subfamily B, PCDHGB2 (Protocadherin gamma B2) is a 931 amino acid protein that is one of 22 proteins encoded by the protocadherin gamma cluster. 
Typical of gamma protocadherins, PCDHGB2 contains six cadherin motifs and is a type I transmembrane receptor expressed in the central nervous system. With localization to synapses, members of the gamma cluster of protocadherins are essential for neuronal survival. There are two isoforms of PCDHGB2 that are produced as a result of alternative splicing events.