Anti-Gαi Rabbit Polyclonal Antibody-抗體-抗體-生物在線
武漢紐斯特生物技術有限公司
Anti-Gαi Rabbit Polyclonal Antibody

Anti-Gαi Rabbit Polyclonal Antibody

商家詢價

產品名稱： Anti-Gαi Rabbit Polyclonal Antibody

英文名稱： Anti-Gαi Rabbit Polyclonal Antibody

產品編號： 21006

產品價格： null

產品產地： 美國

品牌商標： NewEastbio

更新時間： null

使用范圍： ELISA, WB, IHC

武漢紐斯特生物技術有限公司
  • 聯系人 :
  • 地址 : 武漢市東湖新技術開發區光谷生物城B3-3棟2-3樓
  • 郵編 : 430074
  • 所在區域 : 湖北
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  • 郵箱 : neweast3@126.com

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Gαi [21006]
[100 μL]		 ?

Catalog Number:??21006
Gene Symbol:??Gα i
Description: ??Anti-Gα i Rabbit Polyclonal Antibody
Background: ??Heterotrimeric G proteins are critical cellular signal transducers. Gα i represents one sub-family of G proteins that could mediate the inhibition of adenylyl cyclases. Other biochemical and physiological functions of Gα i proteins are being explored.
Immunogen: ??Recombinant full length protein of Gα i1
Applications: ??ELISA, WB, IHC
Recommended Dilutions: ??ELISA 1:100-1:5000, WB 1:100-1:2000
Concentration: ??1 mg/ml
Host: ??Rabbit
Format: ??Liquid
Clonality: ??Polyclonal
Isotype: ??
Purity: ??Purified from serum
Storage buffer:
Preservative:??no
Constituents:??PBS (without Mg 2+ and Ca 2+ ), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:??Gα i antibody recognizes Gα i1, Gα i2, and Gα i3 of vertebrates
Storage Conditions:??Store at -20°C. Avoid freeze / thaw cycles
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Western blot:??
Western blot analysis of Gi proteins. Gα i1 plasmid DNA was transiently transfected into HEK-293 cells. Whole-cell lysate was used for western blot with the polyclonal anti- Gα i antibody (cat # 21006).
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Publications:
1.??Identification of novel signalling roles and targets for Galpha and Gbetagamma downstream of the insulin-like growth factor 1 receptor in vascular smooth muscle cells
????Biochem J. 2013 Feb 15;450(1):209-19
2.??CRH activation of different signaling pathways results in differential calcium signaling in human pregnant myometrium before and during labor
????J Clin Endocrinol Metab. 2012 Oct;97(10):E1851-61
3.??CXCR4 activation defines a new subgroup of Sonic hedgehog-driven medulloblastoma
????Cancer Res. 2012 Jan 1;72(1):122-32
4.??Regulation of estradiol and progesterone production by CRH-R1 and -R2 is through divergent signaling pathways in cultured human placental trophoblasts
????Endocrinology. 2012 Oct;153(10):4918-28
5.??WNT-5A stimulates the GDP/GTP exchange at pertussis toxin-sensitive heterotrimeric G proteins
????Cell Signal. 2011 Mar;23(3):550-4
6.??Heterotrimeric Galpha(i) proteins are regulated by lipopolysaccharide and are anti-inflammatory in endotoxemia and polymicrobial sepsis
????Biochim Biophys Acta. 2011 Mar;1813(3):466-72
7.??Estrogen- and xenoestrogen-induced ERK signaling in pituitary tumor cells involves estrogen receptor-α interactions with G protein-αi and caveolin I
????Steroids Volume 77, Issue 5, April 2012, Pages 424–432
8.??Na/H exchanger regulatory factors control parathyroid hormone receptor signaling by facilitating differential activation of G(alpha) protein subunits
????J Biol Chem. 2010 Aug 27;285(35):26976-86
9.??Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7
????Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):628-32
10.??Structural basis for activation of trimeric Gi proteins by multiple growth factor receptors via GIV/Girdin
????Mol Biol Cell. 2014 Nov 5;25(22):3654-71
11.??Canonical and Non-canonical G-protein Signaling Helps Coordinate Actin Dynamics to Promote Macrophage Phagocytosis of Zymosan
????Mol Cell Biol. 2014 Nov 15;34(22):4186-99
12.??Fatty Acid-binding Protein 5 (FABP5) Regulates Cognitive Function Both by Decreasing Anandamide Levels and by Activating the Nuclear Receptor Peroxisome Proliferator-activated Receptor β/δ (PPARβ/δ) in the Brain
J Biol Chem. 2014 May 2;289(18):12748-58