Active人IGF1全長(zhǎng)蛋白質(zhì)
產(chǎn)品名稱: Active人IGF1全長(zhǎng)蛋白質(zhì)
英文名稱: IBP1 IGF I IGF IA IGF IB IGF-I Igf1 IGF1_HUMAN IGFI IGFIA Insulin like growth factor 1 Insulin like growth factor 1 (somatomedin C) Insulin
產(chǎn)品編號(hào): ab9573
產(chǎn)品價(jià)格: 0
產(chǎn)品產(chǎn)地: 英國(guó)
品牌商標(biāo): abcam
更新時(shí)間: null
使用范圍: null
- 聯(lián)系人 :
- 地址 : 深圳市寶安區(qū)西鄉(xiāng)寶民二路賢基大廈4E
- 郵編 :
- 所在區(qū)域 : 廣東
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- 郵箱 : 1484332550@qq.com
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- 性質(zhì)Recombinant
- 來(lái)源E. coli
- 氨基酸序列
- AccessionP05019
- 種屬Human
- 序列GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFR SCDLRRLEMYCAPLKPAKSA
- 分子量8 kDa
- 氨基酸49 to 118
技術(shù)指標(biāo)
Our?Abpromise guarantee?covers the use of?ab9573?in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 應(yīng)用
Functional Studies
SDS-PAGE
- 內(nèi)毒素水平< 0.100?Eu/μg
- 形式Lyophilised
- 補(bǔ)充說(shuō)明The biological activity is determined by its ability to stimulate the proliferation of mouse FDC-P1 cells. The ED50?was determined by a cell proliferation assay using FDC-P1 cells is < 2.0 ng/ml, corresponding to a specific activity of > 5 x 105 units/mg. Reconstitute in water.
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濃度由溶解方法決定 由溶解方法決定?
制備和貯存
- 穩(wěn)定性和存儲(chǔ)
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
n/a
This product is an active protein and may elicit a biological response in vivo, handle with caution.
- 復(fù)溶Reconstitute with 100 ul of deionised water (or equivalent Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary.
常規(guī)信息
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別名
- IBP1
- IGF I
- IGF IA
see all - 功能The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake.
- 疾病相關(guān)Defects in IGF1 are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) [MIM:608747]. IGF1 deficiency is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation.
- 序列相似性Belongs to the insulin family.
- 細(xì)胞定位Secreted.
- ?
