人IL10 蛋白|Human IL10 Protein, His Tag
產(chǎn)品名稱： 人IL10 蛋白|Human IL10 Protein, His Tag
英文名稱： Human IL10 Protein, His Tag
產(chǎn)品編號： PME101160
產(chǎn)品價格： 0
產(chǎn)品產(chǎn)地： China
品牌商標： DIMA Biotech
更新時間： null
使用范圍： null
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The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, May 2020]