Anti-Nav1.1 mAb: ATTO 488 [S74-71]
產品名稱： Anti-Nav1.1 mAb: ATTO 488 [S74-71]
英文名稱： Nav1.1 Monoclonal Antibody: ATTO 488 [S74-71]
產品編號： SMC-376D-A488
產品價格： null
產品產地： 加拿大
品牌商標： StressMarq
更新時間： null
使用范圍： WB, IHC, IP
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Voltage gated sodium channels initiate action potentials in neurons. Nav1.1 is abundant in the adult brain, and primarily localized in cell bodies. Mutations in the Nav1.1 channels cause generalized epilepsy with febrile seizures plus (GEFS+). Studies show that Nav1.1 channels also play a crucial role in the excitability of cerebellar Purkinje neurons, with major contributions to peak, persistent and resurgent forms of sodium current and to sustained action potential firing (3).