Anti-TASK1 Potassium Channel mAb [S374-48]
產(chǎn)品名稱： Anti-TASK1 Potassium Channel mAb [S374-48]
英文名稱： TASK1 Potassium Channel Monoclonal Antibody [S374-48]
產(chǎn)品編號(hào)： SMC-473D
產(chǎn)品價(jià)格： null
產(chǎn)品產(chǎn)地： 加拿大
品牌商標(biāo)： StressMarq
更新時(shí)間： null
使用范圍： WB, ICC, IHC
StressMarq
- 聯(lián)系人 :
- 地址 : 加拿大
- 郵編 :
- 所在區(qū)域 : 其他
- 電話 : 138****6620; 點(diǎn)擊查看
- 傳真 : 點(diǎn)擊查看
- 郵箱 : hedyl@stressmarq.com
K+ channels are divided into three subclasses reflecting the number of transmembrane segments (TMS), which are designated 6TMS, 4TMS and 2TMS. Members of the 4TMS class contain two distinct pore regions and include TWIK, TREK, TRAAK and TASK. TASK channels are highly sensitive to external pH in the physiological range. TASK-1 is expressed in brain and in rat heart, with high levels of expression in the right atrium. TASK-2, mainly expressed in kidney, is localized in cortical distal tubules and collecting ducts, suggesting a role in renal K+ transport. TASK-3 from rat cerebellum shares 54% identity with TASK-1, but less than 30% identity with TASK-2 and other tandem pore K+ channels.