PAK1 polyclonal antibody
產(chǎn)品名稱： PAK1 polyclonal antibody
英文名稱： PAK1 polyclonal antibody
產(chǎn)品編號： PAB18877
產(chǎn)品價格： null
產(chǎn)品產(chǎn)地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯(lián)系人 :
- 地址 : 臺灣臺北市內(nèi)湖區(qū)洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區(qū)域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of PAK1.
- Immunogen:
- A synthetic peptide corresponding to 15 amino acids at N-terminus of human PAK1.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Storage Buffer:
- In buffer containing 0.02% sodium azide
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:20000-1:80000)
Western Blot (1:200-1:500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 5058
- Protein Accession#:
- NM_002576
- Gene Name:
- PAK1
- Gene Alias:
- MGC130000,MGC130001,PAKalpha
- Gene Description:
- p21 protein (Cdc42/Rac)-activated kinase 1
- Omim ID:
- 602590
- Gene Ontology:
- Hyperlink
- Gene Summary:
- PAK proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology. Alternativelt spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- STE20 homolog, yeast,p21-activated kinase 1,p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast),p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related)
- Gene Pathway
- Axon guidance
- Chemokine signaling pathway
- Epithelial cell signaling in Helicobacter pylori infection
- ErbB signaling pathway
- Fc gamma R-mediated phagocytosis
- Focal adhesion
- MAPK signaling pathway
- Natural killer cell mediated cytotoxicity
- Regulation of actin cytoskeleton
- Renal cell carcinoma
- T cell receptor signaling pathway