B3GALNT1 Rabbit pAb (APR27670N)
產品名稱: B3GALNT1 Rabbit pAb (APR27670N)
英文名稱: B3GALNT1 Rabbit pAb (APR27670N)
產品編號: APR27670N
產品價格: null
產品產地: 美國
品牌商標: Leading Biology
更新時間: null
使用范圍:
分子量:Calculated MW: 39kDa Observed MW: 45kDa 細胞定位:Golgi apparatus membrane, Single-pass type II membrane protein 稀釋方法:WB 1:500 - 1:2000 IF 1:50 - 1:200 總結:This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). The encoded protein of this gene does not use N-acetylglucosamine as an acceptor sugar at all.
