Size??100ug
Cat code??200607
Species Cross-reactivity??H,M
Key Application??WB
Host??Mouse
Antibody type??Monoclonal antibody
Purified method??Affinity purified
Isotype??IgG1
Molecular Weight??45kDa
Sensitivity??This antibody detects endogenous levels of JUN and does not cross-react with related proteins.
Immunogen??Purified recombinant human JUN protein fragments expressed in E.coli.
UniProt Number??P05412
GeneBank ID??NM_002228
Subcellular location??Nucleus.
Formulation??Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol
Altername??jun oncogene,activator protein 1,proto-oncogene c-Jun,enhancer-binding protein AP1,Jun activation domain binding protein,v-jun sarcoma virus 17 oncogene homolog,v-jun avian sarcoma virus 17 oncogene homolog
Gene_symbol??AP1; AP-1; c-Jun
Summary??This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq, Jul 2008]
UniPort summary  Function??Transcription factor that recognizes and binds to the enhancer heptamer motif 5′-TGA[CG]TCA-3′. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
Application Images :??
Western blot detection of JUN  in :293 &3T3 cell lysates(1:1000 diluted).  
Predicted band size: 36KDa       
Observed band size: 45KDa.