AGT monoclonal antibody (M01), clone 1A10
產品名稱: AGT monoclonal antibody (M01), clone 1A10
英文名稱: AGT monoclonal antibody (M01), clone 1A10
產品編號: H00000183-M01
產品價格: null
產品產地: 臺灣
品牌商標: Abnova
更新時間: null
使用范圍:
亞諾法生技股份有限公司(Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant AGT.
- Immunogen:
- AGT (AAH11519, 376 a.a. ~ 485 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- TIHLTMPQLVLQGSYDLQDLLAQAELPAILHTELNLQKLSNDRIRVGEVLNSIFFELEADEREPTESTQQLNKPEVLEVTLNRPFLFAVYDQSATALHFLGRVANPLSTA
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG1 lambda
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.

Western Blot detection against Immunogen (37.73 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- A haplotype of human angiotensinogen gene containing -217A increases blood pressure in transgenic mice as compared to -217G.
Jain S, Vinukonda G, Fiering SN, Kumar A.Am J Physiol Regul Integr Comp Physiol. 2008 Dec;295(6):R1849-57. Epub 2008 Oct 22.
- 2.
- HNF-1 alpha plays an important role in IL-6 induced expression of the Human Angiotensinogen Gene.
Jain S, Li Y, Patil S, Kumar A.Am J Physiol Cell Physiol. 2007 Jul;293(1):C401-10. Epub 2007 May 2.
- Applications
- Western Blot (Cell lysate)

- AGT monoclonal antibody (M01), clone 1A10 Western Blot analysis of AGT expression in HepG2 ( Cat # L019V1 ).
- Protocol Download
- Western Blot (Transfected lysate)

- Western Blot analysis of AGT expression in transfected 293T cell line by AGT monoclonal antibody (M01), clone 1A10.
Lane 1: AGT transfected lysate(53 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Sandwich ELISA (Recombinant protein)

- Detection limit for recombinant GST tagged AGT is approximately 1ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 183
- GeneBank Accession#:
- BC011519
- Protein Accession#:
- AAH11519
- Gene Name:
- AGT
- Gene Alias:
- ANHU,FLJ92595,FLJ97926,SERPINA8
- Gene Description:
- angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq
- Other Designations:
- OTTHUMP00000035878,alpha-1 antiproteinase, antitrypsin,angiotensin I,angiotensin II,angiotensinogen,pre-angiotensinogen,serine (or cysteine) proteinase inhibitor
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