氨基末端激酶3重組兔單克隆抗體
產品名稱： 氨基末端激酶3重組兔單克隆抗體
英文名稱： JNK3
產品編號： YJ-52929
產品價格： null
產品產地： 上海
品牌商標： 雅吉
更新時間： null
使用范圍： WB, IF, ICC
上海雅吉生物科技有限公司
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?中文名稱?氨基末端激酶3重組兔單克隆抗體?別? ? 名 c Jun kinase 3; c-Jun N-terminal kinase 3; cJun N terminal kinase 3; FLJ12099; FLJ33785; JNK3 alpha protein kinase; JNK3A; MAP kinase 10; MAP kinase; MAP kinase p49 3F12; MAPK 10; Mapk10; MGC50974; mitogen activated protein kinase 10; Mitogen-activated protein kinase 10; MK10_HUMAN; p493F12; p54bSAPK; PRKM10; protein kinase mitogen activated 10; SAPK1b; Stress activated protein kinase 1b; stress activated protein kinase beta; Stress activated protein kinase JNK3; Stress-activated protein kinase JNK3.? ?研究領域 腫瘤? 神經生物學? 信號轉導? 細胞凋亡? 轉錄調節因子? 激酶和磷酸酶? ?抗體來源 Rabbit?克隆類型 Monoclonal?克 隆 號 3A1?交叉反應 Human,??產品應用 WB=1:500-2000 ICC=1:100-500 IF=1:100-500?not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.?分 子 量 53kDa?細胞定位 細胞核 細胞漿 細胞膜??性? ? 狀 Liquid?濃? ? 度 1mg/ml?免 疫 原 Recombinant human JNK3 protein (400-500aa):??亞? ? 型 IgG?純化方法 affinity purified by Protein A?儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.?保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.?PubMed PubMed?產品介紹 MAPK10 (JNK3) is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuron-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways of neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 (CDK5) can phosphorylate and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.?Subunit:Interac