HLA-A2 monoclonal antibody, clone BB7.2
產品名稱： HLA-A2 monoclonal antibody, clone BB7.2
英文名稱： HLA-A2 monoclonal antibody, clone BB7.2
產品編號： MAB6434
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against HLA-A2.
- Immunogen:
- HLA-A2 solubilised by papain.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- This antibody recognizes an epitope at the C-terminus of alpha-2 helix and a turn onone of the underlying beta strands within the human HLA-A2 histocompatibility antigen.
- Form:
- Liquid
- Concentration:
- 1 mg/mL
- Isotype:
- IgG2b
- Storage Buffer:
- In PBS, pH 7.4 (15 mM sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- A simplified PCR-SSP method for HLA-A2 subtype in a population of Wuhan, China.
Liang B, Zhu L, Liang Z, Weng X, Lu X, Zhang C, Li H, Wu X.Cell Mol Immunol. 2006 Dec;3(6):453-8.
- 2.
- Induction of ovarian tumor-specific CD8+ cytotoxic T lymphocytes by acid-eluted peptide-pulsed autologous dendritic cells.
Santin AD, Bellone S, Ravaggi A, Pecorelli S, Cannon MJ, Parham GP.Obstet Gynecol. 2000 Sep;96(3):422-30.
- 3.
- Isolation of broadly reactive, tumor-specific, HLA Class-I restricted CTL from blood lymphocytes of a breast cancer patient.
Verdegaal EM, Huinink DB, Hoogstraten C, Marijnissen AK, Gorsira MB, Claas FH, Osanto S.Hum Immunol. 1999 Dec;60(12):1195-206.
- Application Image
- Immunoprecipitation
- Flow Cytometry
- Entrez GeneID:
- 3105
- Gene Name:
- HLA-A
- Gene Alias:
- HLAA
- Gene Description:
- major histocompatibility complex, class I, A
- Gene Ontology:
- Hyperlink
- Gene Summary:
- HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described. [provided by RefSeq
- Other Designations:
- HLA class I histocompatibility antigen, A-23 alpha chain,MHC class I antigen HLA-A heavy chain,MHC leukocyte antigen,OTTHUMP00000161059,antigen presenting molecule,leucocyte antigen class I,leukocyte antigen class I-A
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