PeproTech大鼠抗人/小鼠CD11b PE
產品名稱: PeproTech大鼠抗人/小鼠CD11b PE
英文名稱: Anti-Human/Mouse CD11b PE
產品編號: 03221-60-25
產品價格: null
產品產地: USA
品牌商標: peperotech(BioGems)
更新時間: null
使用范圍: 流式
美國PeproTech(派普泰克)公司中國代表處
- 聯系人 :
- 地址 :  江蘇省蘇州市工業園區星湖街218號A1北座4樓L03
- 郵編 : 215123
- 所在區域 : 江蘇
- 電話 : 點擊查看
- 傳真 : 點擊查看
- 郵箱 : peprotech.infochina@thermofisher.com
The M1/70 monoclonal antibody specifically reacts with the 170 kDa αM integrin chain of mouse CD11b from the Mac-1 integrin (CD11b/CD18). Mac-1 binds to C3bi, CD54 (ICAM-1), and fibrinogen, and it is expressed by granulocytes, macrophages, NK cells, myeloid-derived dendritic cells, microglia, activated lymphocytes, and mouse B-1 cells. The expression is up-regulated on activated neutrophils at the same time that L-selectin is shed from the cell surface. The M1/70 antibody is used for the detection of monocytes, granulocytes, and a subset of natural killer cells in human peripheral blood. M1/70 blocks C3bi binding and cell adherence, but not cell-mediated lysis and it cross-reacts with human CD11b.
