Anti-Versican mAb: ATTO 565 [S351-23]
產(chǎn)品名稱(chēng)： Anti-Versican mAb: ATTO 565 [S351-23]
英文名稱(chēng)： Versican Monoclonal Antibody: ATTO 565 [S351-23]
產(chǎn)品編號(hào)： SMC-439D-A565
產(chǎn)品價(jià)格： null
產(chǎn)品產(chǎn)地： 加拿大
品牌商標(biāo)： StressMarq
更新時(shí)間： null
使用范圍： WB, ICC
StressMarq
- 聯(lián)系人 :
- 地址 : 加拿大
- 郵編 :
- 所在區(qū)域 : 其他
- 電話(huà) : 138****6620; 點(diǎn)擊查看
- 傳真 : 點(diǎn)擊查看
- 郵箱 : hedyl@stressmarq.com
Versican (chondroitin sulfate proteoglycan 2) is a large extracellular matrix proteoglycan involved in cell growth and differentiation. Important as a structural molecule, versican creates loose and hydrated matrices during key events in development and disease. The protein contains hyaluronic acid and glycosminoglycan-binding domains, epidermal growth factor-like repeats, a Lectinlike sequence and a complement regulatory protein-like domain. Splice variants differ greatly in length and degree of modification by glycoaminoglycan chains. Accumulation around smooth muscle cells in lesions of athero-sclerosis suggests a role for versican in atherogenesis. Versican, differentially expressed in human melanoma, plays a role in tumor development and may be a reliable marker for clinical diagnosis. The organization of HA- and versican-rich pericellular matrices may faciliatate migration and mitosis by diminishing cell surface adhesivity and affecting cell shape through steric exclusion and the viscous properties of HA proteoglycan gels.