Recombinant Cynomolgus TL1A Protein,His Tag
產品名稱: Recombinant Cynomolgus TL1A Protein,His Tag
英文名稱: Recombinant Cynomolgus TL1A Protein,His Tag
產品編號: 94078ES
產品價格: 詢價
產品產地: Yeasen
品牌商標: Yeasen
更新時間: 2026-02-11T13:44:32
使用范圍: null
- 聯系人 : 李自轉
- 地址 : 上海市浦東新區天雄路166弄一號樓三層南單元
- 郵編 : 200030
- 所在區域 : 上海
- 電話 : 139****5640 點擊查看
- 傳真 : 點擊查看
- 郵箱 : lizizhuan@yeasen.com
- 二維碼 : 點擊查看
Tumor necrosis factor (TNF)-like cytokine 1A (TL1A) is a member of the TNF superfamily of proteins (TNFSF15), which signals through association with death domain receptor 3 (DR3). Decoy receptor 3 (DcR3) competes with DR3 for TL1A binding and inhibits functional signaling. These proteins are significantly upregulated in inflamed intestinal tissues, and their pathogenetic importance for inflammatory bowel disease (IBD) is suggested by accumulating evidence.TL1A/DR3 induce costimulatory signals to activated lymphocytes, including the gut-specific populations of CD4+CD161+ and CD4+CCR9+ cells, affecting all majoreffector pathways and inducing the mucosal upregulation of Th1, Th2, and Th17 factors.
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產品別稱
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TNFSF15,VEGI,TL1,TL1A,TNLG1B,VEGI192A
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種屬
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Cynomolgus
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表達序列
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Leu72-Leu251
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Accession
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F6S8F9-1
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標簽
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N-His Tag
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表達系統
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HEK293
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分子量
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The protein has a predicted MW of 20.5 kDa
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純度
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> 90% as determined by SDS-PAGE
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內毒素
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< 1.0 EU per μg by the LAL method.
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制劑
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Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
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外觀
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Liquid
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生物活性
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ELISA: Cynomolgus TL1A Protein; His Tag was immobilized at 5 μg/ml (100 μL/well). Increasing concentrations of Monoclonal Anti-HumanTNFSF15(TL1A) hIgG1 Antibody were added.
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高純度、高活性、低內毒素、高批間一致性
SDS-PAGE


Figure 1. On SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Bioactivity-ELISA


Figure 2.Cynomolgus TL1A Protein; His Tag was immobilized at 5 μg/ml (100 μL/well). Increasing concentrations of Monoclonal Anti-HumanTNFSF15(TL1A) hIgG1 Antibody were added.
-85 ~ -65℃保存,收到貨之日起,6個月有效期。避免反復凍融,建議等分分裝為一次實驗使用量,分裝后,-80℃凍存。
