Size??100ug
Cat code??200296
Species Cross-reactivity??H
Key Application??WB,ICC
Host??Mouse
Antibody type??Monoclonal antibody
Purified method??Affinity purified
Isotype??IgG2b
Molecular Weight??55kDa
Sensitivity??This antibody detects endogenous levels Keratin 7 and does not cross-react with related proteins.
Immunogen??Purified recombinant human Keratin 7 protein fragments expressed in E.coli.
UniProt Number??P08729
GeneBank ID??NM_005556
Subcellular location??Cytoplasm
Formulation??Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Altername??K7; CK7; SCL; K2C7; MGC3625; MGC129731
Gene_symbol??K7; CK7; SCL; K2C7
Summary??The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia 
ining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described.
UniPort summary  Function??Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
Application Images :??
Western blot detection of Keratin 7(C-terminus) antibody in T47D&Hela Lung cell lysates using Keratin 7(C-terminus) antibody (1:1000 diluted).
Predicted band size: 51KDa
Observed band size: 55KDa.
Immunocytochemistry of HeLa cells using anti- Keratin 7(C-terminus) antibody diluted 1:150.