RET polyclonal antibody
產品名稱： RET polyclonal antibody
英文名稱： RET polyclonal antibody
產品編號： PAB3380
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of RET.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human RET.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- siRNA nanoformulation against the ret/PTC1 junction oncogene is efficient in an in vivo model of papillary thyroid carcinoma.
de Martimprey H, Bertrand JR, Fusco A, Santoro M, Couvreur P, Vauthier C, Malvy C.Nucleic Acids Res. 2008 Jan;36(1):e2. Epub 2007 Dec 13.
- Entrez GeneID:
- 5979
- Protein Accession#:
- NP_066124;P07949
- Gene Name:
- RET
- Gene Alias:
- CDHF12,HSCR1,MEN2A,MEN2B,MTC1,PTC,RET-ELE1,RET51
- Gene Description:
- ret proto-oncogene
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq
- Other Designations:
- RET transforming sequence,cadherin family member 12,hydroxyaryl-protein kinase,oncogene RET,receptor tyrosine kinase,ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)
- Gene Pathway
- Related Disease
- Adenocarcinoma
- Adenocarcinoma, Follicular
- Adenocarcinoma, Papillary
- Adenoma
- Adrenal Gland Neoplasms
- Alzheimer Disease
- Atherosclerosis
- Atherosclerosis
- Carcinoma
- Carcinoma, Medullary
- Carcinoma, Papillary
- Carcinoma, Papillary, Follicular
- Cleft Lip
- Cleft Palate
- Digestive System Abnormalities
- Disease Progression
- Down Syndrome
- Endocrine Gland Neoplasms
- Esophageal Neoplasms