BSG monoclonal antibody, clone MEM-M6/1 (Biotin)
產(chǎn)品名稱： BSG monoclonal antibody, clone MEM-M6/1 (Biotin)
英文名稱： BSG monoclonal antibody, clone MEM-M6/1 (Biotin)
產(chǎn)品編號(hào)： MAB5048
產(chǎn)品價(jià)格： null
產(chǎn)品產(chǎn)地： 臺(tái)灣
品牌商標(biāo)： Abnova
更新時(shí)間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯(lián)系人 :
- 地址 : 臺(tái)灣臺(tái)北市內(nèi)湖區(qū)洲子街 108 號(hào) 9 樓
- 郵編 : 11493
- 所在區(qū)域 : 臺(tái)灣
- 電話 : +886-920**1152 點(diǎn)擊查看
- 傳真 : 點(diǎn)擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against recombinant BSG.
- Immunogen:
- Recombinant Fc fusion protein corresponding to BSG.
- Host:
- Mouse
- Theoretical MW (kDa):
- 50-60
- Reactivity:
- Human
- Specificity:
- This antibody recognizes an epitope in the N-terminal Ig domain (D1) of CD147 (Neurothelin), a 50-60 KDa type I transmembrane glycoprotein primarily expressed on all leukocytes, red blood cells, platelets and endothelial cells; it is not expressed by resting lymphocytes. This antibody is a high-affinity antibody capable of binding to unstimulated peripheral blood T cells.
- Form:
- Liquid
- Conjugation:
- Biotin
- Concentration:
- 1 mg/mL
- Isotype:
- IgG1
- Storage Buffer:
- In PBS, pH 7.4 (15 mM sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Flow Cytometry (1:250)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Extracellular matrix metalloproteinase inducer (CD147) is a novel receptor on platelets, activates platelets, and augments nuclear factor kappaB-dependent inflammation in monocytes.
Schmidt R, Bultmann A, Fischel S, Gillitzer A, Cullen P, Walch A, Jost P, Ungerer M, Tolley ND, Lindemann S, Gawaz M, Schomig A, May AE.Circ Res. 2008 Feb 15;102(3):302-9. Epub 2007 Nov 29.
- 2.
- Cyclophilin B induces integrin-mediated cell adhesion by a mechanism involving CD98-dependent activation of protein kinase C-delta and p44/42 mitogen-activated protein kinases.
Melchior A, Denys A, Deligny A, Mazurier J, Allain F.Exp Cell Res. 2008 Feb 1;314(3):616-28. Epub 2007 Nov 17.
- 3.
- T cell activation-associated epitopes of CD147 in regulation of the T cell response, and their definition by antibody affinity and antigen density.
Koch C, Staffler G, Huttinger R, Hilgert I, Prager E, Cerny J, Steinlein P, Majdic O, Horejsi V, Stockinger H.Int Immunol. 1999 May;11(5):777-86.
- Application Image
- Flow Cytometry
- Entrez GeneID:
- 682
- Gene Name:
- BSG
- Gene Alias:
- 5F7,CD147,EMMPRIN,M6,OK,TCSF
- Gene Description:
- basigin (Ok blood group)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. The encoded protein is also a member of the immunoglobulin superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- CD147 antigen,M6 leukocyte activation antigen,OK blood group antigen,basigin,collagenase stimulatory factor,extracellular matrix metalloproteinase inducer
- Related Disease