Recombinant Rat IL-4
產品名稱： Recombinant Rat IL-4
英文名稱： Recombinant Rat IL-4
產品編號： 400-04
產品價格： 0
產品產地： USA
品牌商標： PEPROTECH
更新時間： null
使用范圍： null
上海研卉生物科技有限公司
- 聯系人 :
- 地址 : 上海市嘉定區葉城路1288號
- 郵編 :
- 所在區域 : 上海
- 電話 : 187****6455 點擊查看
- 傳真 : 點擊查看
- 郵箱 : yanhuibio@163.com
產品編號:
400-04
別名:
BCGF, BCDF, B cell stimulating factor (BSF-1)
描述:
IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant rat IL-4 is a 14.0 kDa globular protein containing 126 amino acid residues.
氨基酸序列:
MHGCNDSPLR EIINTLNQVT EKGTPCTEMF VPDVLTATRN TTENELICRA SRVLRKFYFP RDVPPCLKNK SGVLGELRKL CRGVSGLNSL RSCTVNESTL TTLKDFLESL KSILRGKYLQ SCTSMS
來源:
E.coli
純度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
生物活性:
Tested by its ability to suppress LPS-induced TNF-α and MIP-2 production in mouse splenocytes.
?
?
?
?
交叉反應:
Mouse