LRRK2 polyclonal antibody
產品名稱： LRRK2 polyclonal antibody
英文名稱： LRRK2 polyclonal antibody
產品編號： PAB2629
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of LRRK2.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to residues surrounding L893 of human LRRK2.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Dynamic and redundant regulation of LRRK2 and LRRK1 expression.
Biskup S, Moore DJ, Rea A, Lorenz-Deperieux B, Coombes CE, Dawson VL, Dawson TM, West AB.BMC Neurosci. 2007 Nov 28;8:102.
- Application Image
- Immunohistochemistry
- ELISA
- Entrez GeneID:
- 120892
- Protein Accession#:
- XP_058513
- Gene Name:
- LRRK2
- Gene Alias:
- AURA17,DARDARIN,PARK8,RIPK7,ROCO2
- Gene Description:
- leucine-rich repeat kinase 2
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq
- Other Designations:
- Parkinson disease (autosomal dominant) 8,augmented in rheumatoid arthritis 17
- Gene Pathway
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Aphasia, Primary Progressive
- Chromosome Aberrations
- Cognition
- Cognition Disorders
- Crohn Disease
- Dementia
- Disease Progression
- Dominance, Cerebral
- Dyskinesias
- Dystonic Disorders
- Essential Tremor
- Essential tremor
- Functional Laterality
- Gaucher disease
- Genetic Predisposition to Disease
- Heredodegenerative Disorders, Nervous System
- Huntington Disease