Size??100ug
Cat code??200287
Species Cross-reactivity??H,R
Key Application??WB,ICC
Host??Mouse
Antibody type??Monoclonal antibody
Purified method??Affinity purified
Isotype??IgG1
Molecular Weight??54kDa
Sensitivity??This antibody detects endogenous levels of MPI and does not cross-react with related proteins.
Immunogen??Purified recombinant human MPI protein fragments expressed in E.coli.
UniProt Number??P34949
GeneBank ID??NM_002435.1
Subcellular location??Cytoplasm
Formulation??Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Altername??Phosphohexomutase；Phosphomannose isomerase，Short name=PMI
Gene_symbol??PMI; PMI1; CDG1B
Summary??Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib.
UniPort summary  Function??Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
Application Images :??

Western blot detection of MPI in Rat kidney,Rat brain，A549&LNCAP cell lysates and  using MPI antibody (1:1000 diluted). Predicted band size: 54KDa Observed band size: 45KDa
Immunocytochemistry stain of Hela using MPI antibody (1:300).