STK39 polyclonal antibody
產品名稱： STK39 polyclonal antibody
英文名稱： STK39 polyclonal antibody
產品編號： PAB16584
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of STK39.
- Immunogen:
- A synthetic peptide corresponding to C-terminus 19 amino acids of human STK39.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Characterization of SPAK and OSR1, regulatory kinases of the Na-K-2Cl cotransporter.
Gagnon KB, England R, Delpire E.Mol Cell Biol. 2006 Jan;26(2):689-98.
- 2.
- SPAK kinase is a substrate and target of PKCtheta in T-cell receptor-induced AP-1 activation pathway.
Li Y, Hu J, Vita R, Sun B, Tabata H, Altman A.EMBO J. 2004 Mar 10;23(5):1112-22. Epub 2004 Feb 26.
- 3.
- The Ste20 group kinases as regulators of MAP kinase cascades.
Dan I, Watanabe NM, Kusumi A.Trends Cell Biol. 2001 May;11(5):220-30.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of STK39 in SK-N-SH cell lysate with STK39 polyclonal antibody (Cat # PAB16584) at (A) 1 and (B) 2 ug/mL .
- Entrez GeneID:
- 27347
- Protein Accession#:
- NP_037365
- Gene Name:
- STK39
- Gene Alias:
- DCHT,DKFZp686K05124,PASK,SPAK
- Gene Description:
- serine threonine kinase 39 (STE20/SPS1 homolog, yeast)
- Omim ID:
- 607648
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq
- Other Designations:
- Ste20-like protein kinase,proline-alanine-rich STE20-related kinase,small intestine SPAK-like kinase