分子量：Calculated MW: 10kDa/18kDa/40kDa/116kDa
Observed MW: 110KDa

細胞定位：Cytoplasm, cytosol

稀釋方法：WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200

總結：This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants.