Zanubrutinib 1691249-45-2
產品名稱： Zanubrutinib 1691249-45-2
英文名稱： Zanubrutinib
產品編號： 1691249-45-2
產品價格： 0
產品產地： 國外
品牌商標： MEDKOO
更新時間： null
使用范圍： null
- 聯系人 :
- 地址 : 北京市海淀區創客小鎮
- 郵編 :
- 所在區域 : 北京
- 電話 : 133****0421 點擊查看
- 傳真 : 點擊查看
- 郵箱 : customer@bestopbio.com;3007606172@qq.com
Description:?Zanubrutinib, aslo known as BGB-3111, is a potent and highly selective small molecule BTK inhibitor for the potential treatment of a variety of lymphomas. BGB-3111 selectively binds to and inhibits the activity of BTK and prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. Zanubrutinib has CAS#1691249-45-2 which is the S-isomer.
CAS#: 1691249-45-2 (S-isomer)
Chemical Formula: C27H29N5O3
Exact Mass: 471.227
Molecular Weight: 471.561
Elemental Analysis: C, 68.77; H, 6.20; N, 14.85; O, 10.18
Synonym:?BGB-3111; BGB 3111; BGB3111; Zanubrutinib; Brukinsa.
IUPAC/Chemical Name:?(7S)-4,5,6,7-Tetrahydro-7-[1-(1-oxo-2-propen-1-yl)-4-piperidinyl]-2-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
InChi Key:?RNOAOAWBMHREKO-QFIPXVFZSA-N
InChi Code:?InChI=1S/C27H29N5O3/c1-2-23(33)31-16-13-18(14-17-31)22-12-15-29-27-24(26(28)34)25(30-32(22)27)19-8-10-21(11-9-19)35-20-6-4-3-5-7-20/h2-11,18,22,29H,1,12-17H2,(H2,28,34)/t22-/m0/s1
SMILES Code:?O=C(C1=C2NCC[C@@H](C3CCN(C(C=C)=O)CC3)N2N=C1C4=CC=C(OC5=CC=CC=C5)C=C4)N
Appearance:?Solid powder
Purity:?>98% (or refer to the Certificate of Analysis)
Shipping Condition:?Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition:?Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility:?Soluble in DMSO
Shelf Life:?>2 years if stored properly
Drug Formulation:?This drug may be formulated in DMSO
Stock Solution Storage:?0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code:?2934.99.900