PODS® Human BDNF 腦源性神經營養因子
產品名稱： PODS® Human BDNF 腦源性神經營養因子
英文名稱： PODS® Human BDNF (Brain-derived neurotrophic factor)
產品編號： PPH1
產品價格： 0
產品產地： 英國
品牌商標： Cell Guidance Systems
更新時間： null
使用范圍： null
- 聯系人 : 市場部
- 地址 : 上海市奉賢區匯豐西路2082號9幢
- 郵編 : 200120
- 所在區域 : 上海
- 電話 : 189****5545 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@xpbiomed.com
PODS? Human BDNF
 ?? ? ? ? ? ? |
 ?? ? ? ? ? ? |
| PODS? co-crystals? | PODS? co-crystals? |
?
|
CellGS Catalogue Code? ? ? ? |
Product Name?? ? ? ? ? ? ? ? |
Pack Size? ? ? ? ? ? ? |
? ?? |
|
PPH1-50?? ? ? ? ? ? ? ? |
PODS?Human BDNF??? ? ? ? ? ? ? ? |
50 million? ? ? ? ? ?? |
? ? ? ? ?? |
|
PPH1-250?? ? ? ? ? ? ? ? |
PODS?Human BDNF??? ? ? ? ? ? ? ? |
250 million? ? ? ? ?? |
? ? ? ? ? ? ? |
|
PPH1-1000?? ? ? ? ? ? ? ? |
PODS?Human BDNF??? ? ? ? ? ? ? ? |
1 billion? ? ? ? ? ? |
? ? ? ? ?? |
?
PODS 技術
將生長因子包埋進蛋白質晶體（多角體蛋白）中，多角體蛋白能夠保護包埋的生長因子，并維持其穩定性與生物活性，進而持續釋放到細胞培養系統中。
?
?
PODS BDNF 描述
PODS多角體蛋白與BDNF共結晶。BDNF(Brain-derived neurotrophic factor, 腦源性神經營養因子)是一種神經生長因子，它與低親和力神經生長因子受體(LNGFR)和原肌球蛋白受體激酶B (TrkB)結合，支持神經元生長和存活。海馬區BDNF(Brain-derived neurotrophic factor, 腦源性神經營養因子)的表達對長期記憶的儲存和學習至關重要。BDNF(Brain-derived neurotrophic factor, 腦源性神經營養因子)的某些蛋白結構域與NGF和另一種神經營養因子NT-3(神經營養因子-3)的結構域相同。人、小鼠、大鼠和豬BDNF(腦源性神經營養因子)是交叉反應的。
?
PODS BDNF 規格
?
|
PODS BDNF Product ? Details?? ? ? ? ? ? ? ? |
|
|
Length?? ? ? ? ? ? ? ? |
164 aa?? ? ? ? ? ? ? ? |
|
Molecular ? Weight? ? ?? |
37.6 kDa?? ? ? ? ? ? ? ? |
|
Structure?? ? ? ? ? ? ? ? |
Dimer?? ? ? ? ? ? ? ? |
|
Source?? ? ? ? ? ? ? ? |
Spodoptera ? frugiperda (Sf9) cell culture?? ? ? ? ? ? ? ? |
|
Accession ? Number? ? ? |
P23560?? ? ? ? ? ? ? ? |
|
Endotoxin ? Level? ? ? ? |
<0.06 EU/ml ? as measured by gel clot LAL assay?? ? ? ? ? ? ? ? |
|
Formulation?? ? ? ? ? ? ? ? |
PODS? were ? lyophilized from a volatile solution?? ? ? ? ? ? ? ? |
|
Reconstitution?? ? ? ? ? ? ? ? |
PODS? ? co-crystals may be reconstituted at 200 million co-crystals/ml in water. 20% ? glucose has a buoyant density closer to PODS? co-crystals and can be useful ? for aliquoting.?? ? ? ? ? ? ? ? PODS? ? co-crystals are highly stable when stored in aqueous solution (pH range 6 - ? 8).?? ? ? ? ? ? ? ? |
|
Stability and ? Storage? |
Upon receipt, ? store at 4°C. PODS? co-crystals are stable for at least 1 year when dry and 6 ? months when resuspended.?? ? ? ? ? ? ? ? |
?
PODS BDNF 使用建議
PODS? co-crystals provide a depot of proteins which are steadily secreted. It has been estimated that the biological activity of 50 million PODS? co-crystals generates the same peak dose as 3.3 μg of standard recombinant protein. However, at 5 days following the start of seeding the PODS? co-crystals, there are more than 50% of these peak levels still present in the culture system. Ultimately, the amount of PODS? co-crystals that is optimal for a particular experiment should be determined empirically. Based on previous data, we suggest using?50 million PODS? co-crystals in place of 3.3 μg of standard growth factor?as a starting point."
To control for cross-reactivity with cells or as a negative control, we recommend using PODS? growth factors alongside PODS? Empty crystals, as the latter do not contain or release cargo protein.
?
PODS BDNF AA Sequence
MADVAGTSNR DFRGREQRLF NSEQYNYNNS KNSRPSTSLY KKAGLMHSDP ARRGELSVCD SISEWVTAAD KKTAVDMSGG TVTVLEKVPV SKGQLKQYFY ETKCNPMGYT KEGCRGIDKR HWNSQCRTTQ SYVRALTMDS KKRIGWRFIR IDTSCVCTLT IKRGR
?
PODS BDNF Alternative Names
Brain-derived neurotrophic factor, neurotrophin, abrineurin, 腦源性神經營養因子
?
PODS BDNF 文件資料
 PPH1 Datasheet?? ? ? ? ? ? |
PODS User Guide?? ? ? ? ? ? |
PODS MSDS?? ? ? ? ? ? |
?
更多PODS 相關產品：PODS 生長因子
?
相關文章
PODS促進治療性蛋白傳遞:?PODS BMP-2刺激體內骨再生
干細胞分化和類器官培養新技術--新型緩釋細胞因子技術