Anti-Gα13 Mouse Monoclonal Antibody-抗體-抗體-生物在線

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武漢紐斯特生物技術(shù)有限公司
Anti-Gα13 Mouse Monoclonal Antibody

Anti-Gα13 Mouse Monoclonal Antibody

商家詢價(jià)

產(chǎn)品名稱： Anti-Gα13 Mouse Monoclonal Antibody

英文名稱： Anti-Gα13 Mouse Monoclonal Antibody

產(chǎn)品編號： 26004

產(chǎn)品價(jià)格： null

產(chǎn)品產(chǎn)地： 美國

品牌商標(biāo)： NewEastbio

更新時(shí)間： null

使用范圍： ELISA, WB, IHC, IP

武漢紐斯特生物技術(shù)有限公司
  • 聯(lián)系人 :
  • 地址 : 武漢市東湖新技術(shù)開發(fā)區(qū)光谷生物城B3-3棟2-3樓
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  • 所在區(qū)域 : 湖北
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Gα13 [26004]
[100 μL]		 ?

Catalog Number:??26004
Gene Symbol:??Gna13
Description: ??Anti-Gα13 Mouse Monoclonal Antibody
Background: ??Heterotrimeric G proteins are essential cellular signal transducers. Gα13 is one of the G proteins that could mediate cell migration and angiogenesis. Other biochemical and physiological functions of Gα13 are being explored.
Immunogen: ??Recombinant full length Gα13 protein
Applications: ??ELISA, WB, IHC
Recommended Dilutions: ??ELISA 1:1000-1:5000, WB 1:1000-1:2000
Concentration: ??1 mg/ml
Host: ??mouse
Format: ??Liquid
Clonality: ??Monoclonal
Isotype: ??IgG
Purity: ??Purified from ascites
Storage buffer:
Preservative:??no
Constituents:??PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:??Gα13 monoclonal antibody recognizes Gα13 of vertebrates.
Storage Conditions:??Store at -20°C. Avoid freeze / thaw cycles
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Western blot:??
Western blot analysis of Gα13 proteins. Gα13, Gα12 or Gαq plasmid DNAs were transiently transfected into CHO cells (endogenous Gα13 protein was down-regualted by Gα13 siRNA). Whole-cell lysates were used for western blots.
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Publications:
1.??Resistance to inhibitors of cholinesterase-8A (Ric-8A) is critical for growth factor receptor-induced actin cytoskeletal reorganization
????J Biol Chem. 2011 Sep 2;286(35):31055-61
2.??Agonist activation of the G protein-coupled receptor GPR35 involves transmembrane domain III and is transduced via Galpha and beta-arrestin-2
????Br J Pharmacol. 2011 Feb;162(3):733-48
3.??Gα12/13 inhibition enhances the anti-cancer effect of bortezomib through PSMB5 downregulation
????Carcinogenesis (2010)
4.??Suppression of tumor angiogenesis by Galpha(13) haploinsufficiency
????J Biol Chem. 2009 Oct 2;284(40):27409-15

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