PAI-1/Serpin E1 Rabbit pAb (APR26338N)-抗體-抗體-生物在線

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生物谷
PAI-1/Serpin E1 Rabbit pAb (APR26338N)

PAI-1/Serpin E1 Rabbit pAb (APR26338N)

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產品名稱: PAI-1/Serpin E1 Rabbit pAb (APR26338N)

英文名稱: PAI-1/Serpin E1 Rabbit pAb (APR26338N)

產品編號: APR26338N

產品價格: null

產品產地: 美國

品牌商標: Leading Biology

更新時間: null

使用范圍: WB (Homo sapiens, Rattus norvegicus, Bos taurus) ELISA (Homo sapiens)

生物谷
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分子量:Calculated MW: 43kDa/45kDa
Observed MW: 45kDa

細胞定位:Secreted

稀釋方法:WB 1:500 - 1:2000
IF 1:50 - 1:200

總結:This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.