Active HDAC3+NCOR2 complex全長蛋白質-蛋白質/抗原/多肽-試劑-生物在線
深圳市宇德立生物科技有限公司
Active HDAC3+NCOR2 complex全長蛋白質

Active HDAC3+NCOR2 complex全長蛋白質

商家詢價

產品名稱： Active HDAC3+NCOR2 complex全長蛋白質

英文名稱： CTG26 HD 3 HD3 HDAC 3 HDAC3 HDAC3_HUMAN Histone deacetylase 3 NCOR 2 Nuclear receptor co repressor 2 RPD3 RPD3-2 SMAP45 SMRTE SMRTE tau TNRC

產品編號： ab42631

產品價格： 0

產品產地： 英國

品牌商標： abcam

更新時間： null

使用范圍： null

深圳市宇德立生物科技有限公司
  • 聯系人 :
  • 地址 : 深圳市寶安區西鄉寶民二路賢基大廈4E
  • 郵編 :
  • 所在區域 : 廣東
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?

  • 性質Recombinant
  • 來源Baculovirus

技術指標

Our?Abpromise guarantee?covers the use of?ab42631?in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Activity: 110 U/ug. One U =1 pmol/min, Assay condition: 25 mM Tris/Cl, pH8.0, 137 mM NaCl, 2.7 mM KCl, 1 mM MgCl2, and 0.1 mg/ml BSA, 30 uM Biomol substrate (Catalog number KI177), and 1 ng/ul HDAC3/NcoR2. Incubation condition: 30 min at 37oC.
  • 應用

    Inhibition Assay

  • 純度> 90 % by SDS-PAGE.

  • 形式Liquid
  • 補充說明Co-expressed in a Baculovirus infected Sf9 cell expression system.
  • 濃度50 μg 濃度為 1.1 mg/ml?

制備和貯存

  • 穩定性和存儲

    Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 10% Glycerol, 50mM Tris HCl, 20mM Glutathione, 138mM Sodium chloride, pH 8

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常規信息

  • 別名
    • CTG26
    • HD 3
    • HD3
    see all
  • 功能Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1; increases YY1 repression activity. Required to repress transcription of the POU1F1 transcription factor. Acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation.
  • 組織特異性Widely expressed.
  • 序列相似性Belongs to the histone deacetylase family. HD type 1 subfamily.
  • 翻譯后修飾Sumoylated in vitro.
  • 細胞定位Nucleus.