BMPR1B Rabbit pAb (APR23612N)
產(chǎn)品名稱： BMPR1B Rabbit pAb (APR23612N)
英文名稱： BMPR1B Rabbit pAb (APR23612N)
產(chǎn)品編號(hào)： APR23612N
產(chǎn)品價(jià)格： null
產(chǎn)品產(chǎn)地： 美國(guó)
品牌商標(biāo)： Leading Biology
更新時(shí)間： null
使用范圍：
生物谷
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分子量：Calculated MW: 56kDa/60kDa Observed MW: Refer to figures 稀釋方法：IHC 1:50 - 1:100 IF 1:50 - 1:200 總結(jié)：This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]