Anti-FADD Monoclonal Antibody
產(chǎn)品名稱： Anti-FADD Monoclonal Antibody
英文名稱： FADD
產(chǎn)品編號： K001422M
產(chǎn)品價(jià)格： null
產(chǎn)品產(chǎn)地： 北京
品牌商標(biāo)： Solarbio
更新時(shí)間： null
使用范圍： WB
北京索萊寶科技有限公司--實(shí)驗(yàn)室產(chǎn)品
- 聯(lián)系人 :
- 地址 : 北京市通州區(qū)馬駒橋聯(lián)東U谷景盛南四街85A三層
- 郵編 :
- 所在區(qū)域 : 北京
- 電話 : 010-563*1250 點(diǎn)擊查看
- 傳真 : 點(diǎn)擊查看
- 郵箱 : 2748554845@qq.com
The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals.Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor,tumor necrosis factor receptor,TNFRSF25,and TNFSF10/TRAIL-receptor,and thus it participates in the death signaling initiated by these receptors.Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein,which allows it to recruit caspase-8,and thereby activate the cysteine protease cascade.Knockout studies in mice also suggest the importance of this protein in early T cell development.[provided by RefSeq,Jul 2008]