AXL (Human) Recombinant Protein
產品名稱： AXL (Human) Recombinant Protein
英文名稱： AXL (Human) Recombinant Protein
產品編號： P5687
產品價格： 0
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍： null
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
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- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human AXL (NP_001690.2, 464 a.a. - 885 a.a.) partial recombinant protein with GST tag expressed in Baculovirus infected Sf21 cells.
- Theoretical MW (kDa):
- 74
- Form:
- Liquid
- Preparation Method:
- Baculovirus expression system
- Purification:
- Glutathione sepharose chromatography
- Purity:
- 66 % by SDS-PAGE/CBB staining.
- Activity:
- The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorecence-labeled substrate and Mg (or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip?3000.
Substrate : CSKtide. ATP: 100 μM.
- Storage Buffer:
- In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.05% Brij35, 1 mM DTT, 10% glycerol)
- Storage Instruction:
- Store at -80°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Loading 1 ug protein in SDS-PAGE
- Note:
- Result of activity analysis
-
- Application Image
- Functional Study
- SDS-PAGE
- Entrez GeneID:
- 558
- Protein Accession#:
- NP_001690.2
- Gene Name:
- AXL
- Gene Alias:
- JTK11,UFO
- Gene Description:
- AXL receptor tyrosine kinase
- Omim ID:
- 109135
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
- Other Designations:
- AXL transforming sequence/gene,oncogene AXL