Anti-Gα13 Rabbit Polyclonal Antibody-抗體-抗體-生物在線
武漢紐斯特生物技術有限公司
Anti-Gα13 Rabbit Polyclonal Antibody

Anti-Gα13 Rabbit Polyclonal Antibody

商家詢價

產品名稱： Anti-Gα13 Rabbit Polyclonal Antibody

英文名稱： Anti-Gα13 Rabbit Polyclonal Antibody

產品編號： 21005

產品價格： null

產品產地： 美國

品牌商標： NewEastbio

更新時間： null

使用范圍： ELISA, WB, IHC

武漢紐斯特生物技術有限公司
  • 聯系人 :
  • 地址 : 武漢市東湖新技術開發區光谷生物城B3-3棟2-3樓
  • 郵編 : 430074
  • 所在區域 : 湖北
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  • 郵箱 : neweast3@126.com

Gα13 [21005]
[100 μL]		 ?

Catalog Number:??21005
Gene Symbol:??Ga13
Description: ??Anti-Gα13 Rabbit Polyclonal Antibody
Background: ??Heterotrimeric G proteins are essential cellular signal transducers. Gα13 is one of the G proteins that could mediate cell migration and angiogenesis. Other biochemical and physiological functions of Gα13 are being explored.
Immunogen: ??Recombinant full length Gα13 protein
Applications: ??ELISA, WB, IHC
Recommended Dilutions: ??
ELISA 1:100-1:5000
WB 1:100-1:2000
IHC 1:50-1:100
Concentration: ??1 mg/ml
Host: ??Rabbit
Format: ??Liquid
Clonality: ??Polyclonal
Isotype: ??
Purity: ??Purified from serum
Storage buffer:
Preservative:??no
Constituents:??PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:??Gα13 polyclonal antibody recognizes Gα13 of vertebrates.
Storage Conditions:??Store at -20°C. Avoid freeze / thaw cycles
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Western blot:??
Western blot analysis of Gα13 proteins. MEF whole-cell lysates were used for western blot with anti-Gα13 polyclonal antibody (Cat. # 21005).
Immunofluorescence:??
Immunofluorescence of mouse embryonic fibroblast (MEF) cells. Wild-type MEF cells (top panel) and Gα13 double knock-out cells (Gα13 -/-, bottom panel) were fixed and stained with anti-Gα13 polyclonal antibody (Cat. # 21005). Arrows indicate the dorsal ruffle strcture of one cell.

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Publications:
1.??Resistance to inhibitors of cholinesterase-8A (Ric-8A) is critical for growth factor receptor-induced actin cytoskeletal reorganization
????J Biol Chem. 2011 Sep 2;286(35):31055-61
2.??Agonist activation of the G protein-coupled receptor GPR35 involves transmembrane domain III and is transduced via Galpha and beta-arrestin-2
????Br J Pharmacol. 2011 Feb;162(3):733-48
3.??Gα12/13 inhibition enhances the anti-cancer effect of bortezomib through PSMB5 downregulation
????Carcinogenesis (2010)
4.??Suppression of tumor angiogenesis by Galpha(13) haploinsufficiency
????J Biol Chem. 2009 Oct 2;284(40):27409-15

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