?


Human, Murine & Rat Neurotrophins
Recombinant Human CNTF





?





		Synonyms :
Ciliary Neurotrophic Factor



		Description :
CNTF is a potent neural factor that was originally characterized as a vital factor for the survival of chick ciliary neurons in vitro.  CNTF is also important for the survival of other neural cell types including primary sensory neurons, motor neurons, basal forebrain neurons and type 2 astrocytes.  CNTF is highly conserved across species and exhibits cross-species bioactivity.  Recombinant human CNTF is synthesized as a 199 amino acid polypeptide (22.7 kDa) lacking a hydrophobic N-terminal signal for secretion.



		Catalog #:
450-13



		Source :
E.coli



		Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses.



		Endotoxin Level :
Endotoxin level is less than 0.1 ng per μg (1EU/μg).



		Biological Activity :
Determined by its ability to stimulate proliferation of human TF-1 cells using an ED50 concentration range of 50-150 ng/ml.


Selected References :
Selected List of References Citing This PeproTech Product



                AA Sequence :
MAFTEHSPLT PHRRDLCSRS IWLARKLRSD LTALTESYVK HQGLNKNINL DSADGMPVAS TDQWSELTEA ERLQENLQAY RTFHVLLARL LEDQQVHFTP TEGDFHQAIH TLLLQVAAFA YQIEELMILL EYKIPRNEAD GMPINVGDGG LFEKKLWGLK VLQELSQWTV RSIHDLRFIS SHQTGIPARG SHYIANNKKM 



		PubMed Link :
CNTF+AND+human


Country of Origin :
USA
















        Size A
5μg
$80?
?


?



        Size B
20μg
$195?
?


?



        Size C
1mg
$3000?
?


?















Special 
                    Sizes: 
 Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.





Usage:
For Research Use Only.  Not for use in diagnostic or therapeutic procedures.