PTPRN2 monoclonal antibody (M04), clone 2G8
產品名稱： PTPRN2 monoclonal antibody (M04), clone 2G8
英文名稱： PTPRN2 monoclonal antibody (M04), clone 2G8
產品編號： H00005799-M04
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant PTPRN2.
- Immunogen:
- PTPRN2 (NP_002838, 108 a.a. ~ 212 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- ELADLPKTYLRRPEASSPARPSKHSVGSERRYSREGGAALANALRRHLPFLEALSQAPASDVLARTHTAQDRPPAEGDDRFSESILTYVAHTSALTYPPGPRTQL
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG1 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.29 KDa) .
- MSDS:
Download
- Applications
- Western Blot (Recombinant protein)
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged PTPRN2 is 0.1 ng/ml as a capture antibody.
- Protocol Download
- Application Image
- Western Blot (Recombinant protein)
- Sandwich ELISA (Recombinant protein)
- enlarge
- ELISA
- Entrez GeneID:
- 5799
- GeneBank Accession#:
- NM_002847
- Protein Accession#:
- NP_002838
- Gene Name:
- PTPRN2
- Gene Alias:
- IA-2beta,IAR,ICAAR,PTPRP
- Gene Description:
- protein tyrosine phosphatase, receptor type, N polypeptide 2
- Omim ID:
- 601698
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq
- Other Designations:
- IAR/receptor-like protein-tyrosine phosphatase,phogrin,protein tyrosine phosphatase receptor pi,tyrosine phosphatase IA-2 beta
- Gene Pathway
- Related Disease
- Breast cancer
- Breast Neoplasms
- Cardiovascular Diseases
- Cerebral Hemorrhage
- Chromosome Deletion
- Chronic Disease
- Diabetes Mellitus, Type 2
- Edema
- Genetic Predisposition to Disease
- Hypertension
- Intracranial Hemorrhages
- Kidney Diseases
- Kidney Failure, Chronic
- Stroke
- Subarachnoid Hemorrhage
- Tobacco Use Disorder