Anti-CEACAM1 Polyclonal Antibody
產品名稱: Anti-CEACAM1 Polyclonal Antibody
英文名稱: BGP;BGP1;BGPI
產品編號: K006700P
產品價格: null
產品產地: 北京
品牌商標: Solarbio
更新時間: null
使用范圍: WB IHC
北京索萊寶科技有限公司--實驗室產品
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- 地址 : 北京市通州區馬駒橋聯東U谷景盛南四街85A三層
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- 所在區域 : 北京
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This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses.
